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Sirova 1mg Tablet
Last updated on 03 Jul 2026 | 11:21 AM (IST)
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Introduction to Sirova 1mg Tablet
Sirova 1mg Tablet is an immunosuppressant medication containing the active ingredient called Sirolimus. Sirova 1mg Tablet helps prevent organ rejection in people who had a kidney transplant in combination with other medications. Following an organ transplant, our body’s immune system will try to reject the new organ. This medication controls the body’s immune response to accept the transplanted organ.
The Sirova tablet also treats a rare lung disorder called S-LAM (sporadic lymphangioleiomyomatosis). The most common symptom of this disease is shortness of breath. Before taking this medication, you need to talk to your physician if you have liver disorders, intolerance to some sugars, a family history of skin cancer, high cholesterol, or other diseases. Sirova 1mg Tablet is not recommended for adolescents and children under 18 years of age.
Avoid drinking grapefruit juice and eating grapefruits while taking this medication. Limit exposure to the sun while taking this medication. Use sunscreen with high SPF (sun protection factor) and wear protective clothing when you go outside. Avoid live vaccines during the treatment with Sirova 1mg Tablet. Use effective birth control during the treatment and for at least twelve months after the last dose.
Uses of Sirova 1mg Tablet
The Sirova 1mg Tablet is used in the treatment of the following:
- Prevents rejection of kidney transplant
- Sporadic lymphangioleiomyomatosis (lung disease)
Therapeutic Effects of Sirova 1mg Tablet
Sirova 1mg tablet is an immunosuppressant that decreases the activity of your body’s immune system and prevents it from attacking the transplanted organ.
Interaction of Sirova 1mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Sirova 1mg tablet and decrease its effectiveness by causing undesirable side effects.
More Information about Sirova 1mg Tablet
- Keep Sirova 1mg tablet out of sight and reach of children.
- Do not store above 25°C.
How to consume Sirova 1mg Tablet
Always take Sirova 1mg tablet exactly as your physician has told you. Swallow the tablet whole with water. Do not crush or chew the tablets. This medicine must be consistently taken, either with or without food. Avoid drinking grapefruit juice and eating grapefruits while taking this medication.
Safety Advice for Sirova 1mg Tablet
Breast Feeding
Do not breastfeed while taking Sirova 1mg tablet. You need to tell your doctor if you are breastfeeding before taking this medicine.
Alcohol
It is unknown whether consuming alcohol while taking a Sirova 1mg tablet is safe. Please speak with your physician.
Liver
Inform your doctor if you have any history of liver transplantation before starting treatment with the Sirova 1mg tablet. Because it is not recommended to use in such conditions, and medication should be used cautiously in liver disease patients.
Lungs
Inform your doctor if you have any history of lung transplantation before starting treatment with the Sirova 1mg tablet. Because it is not recommended to use it in such conditions, and medication should be used with caution in lung disease patients.
Driving
Taking Sirova 1mg tablet will not impact the body. Talk with your doctor for more information.
Pregnancy
Sirova 1 mg tablet may harm your unborn baby. You need to inform your doctor if you are pregnant or planning to get pregnant before taking this medicine. Use effective birth control during the treatment and for at least twelve months after the last dose.
Side Effects of Sirova 1mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of Sirova 1mg Tablet are:
- Severe allergic reactions (swelling of face, tongue, or mouth, difficulty in breathing)
- Low blood cell counts with kidney damage (haemolytic uraemic syndrome)
- Infections
Common side effects of Sirova 1mg Tablet are:
- Headache
- Fever, pain
- High blood pressure and cholesterol levels
- Constipation, diarrhoea, stomach pain
- Nausea
- Rash
- Infrequent, absent, or heavy periods
- Rapid heart rate
- High blood sugar
- Joint pain
- Acne
- Swelling of the body, including feet and hands.
Word of Advice
Inform your doctor if you have a history of lung or liver transplantation or hypersensitivity. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Avoid live vaccines during the treatment with Sirova 1mg tablet. Notify your doctor immediately if you took any. Use effective birth control during the treatment for atleast twelve months, even after the last dose. This medicine can increase the risk of skin cancer, so use sunscreen protection.
FAQs about Sirova 1mg Tablet
Q1.
Will Sirova 1mg tablet affect fertility?
Sirova 1mg tablet can decrease the sperm count, which returns to the normal state after the treatment. For more fertility concerns, talk with your doctor.
Q2.
Can Sirova 1mg tablet cause any injury to the kidney?
Sirova 1mg can damage the kidney with or without rashes (haemolytic uraemic syndrome). Talk with your doctor before starting this medicine.
Q3.
What should I be aware of before taking Sirova 1mg tablet ?
If you are intolerant to some sugar like lactose and sucrose, inform your doctor before the treatment. And, Sirova 1mg tablet shouldn’t be taken with grapefruit or its juice.
Q4.
Can Sirova 1mg tablet cause diabetics?
Blood sugar levels may be affected by Sirova 1mg tablet. So, regularly check your blood sugar levels, and notify your doctor of any sudden changes.
Q5.
What should I inform my doctor before starting the Sirova 1mg tablet treatment?
Inform your doctor if you have any history of lung or liver transplantation and hypersensitivity because Sirova 1mg tablet is not recommended in such cases.
Fact Box of Sirova 1mg Tablet
Molecule name: Sirolimus | Therapeutic class: Antineoplastics |
Pharmacological class: Immunosuppressants | Indications: 1. Prevents rejection of kidney transplant 2. Sporadic lymphangioleiomyomatosis (lung disease) |
References
- Targeted therapies: Tyrosine kinase inhibitors, monoclonal antibodies, and cytokines, 12th edition, 2011, 1735.
- Pfizer Limited, Electronic medicines compendium (emc), [ Revised on July 2021] [ Accessed on 08th March 2023], https://www.medicines.org.uk/emc/files/pil.1368.pdf
- Pfizer Limited, [ Revised on August 2023] [ Accessed on 08th March 2023],https://labeling.pfizer.com/showlabeling.aspx?id=139.
Disclaimer
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 03 Jul 2026 | 11:21 AM (IST)
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