Quick Summary
Tanstrive 160mg Tablet
Last updated on 06 Oct 2026 | 09:51 AM (IST)
₹177435
MRP: ₹215165
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28 TABLET(s) IN A BOTTLE
Tanstrive 160mg Tablet
Salt Composition
SELPERCATINIB
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Marketer
ELI LILLY AND COMPANY INDIA PVT LTD
18% OFF
₹177435
MRP: ₹2,15,165.00
Inclusive of all taxes
18% Off
Salt Composition
SELPERCATINIB
PAP Offer
Buy 2, Get 1 Free. Contact us for latest updates.
Marketer
ELI LILLY AND COMPANY INDIA PVT LTD
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Introduction
Tanstrive 160mg tablet contains the active constituent Selpercatinib, which belongs to the family of targeted cancer medications known as kinase inhibitors. It blocks abnormal RET proteins that fuel tumour growth, by inhibiting wild-type RET and multiple mutated RET isoforms, along with VEGFR1 and VEGFR3. This tablet is used to treat certain lung, thyroid, and other RET-positive cancers by turning down the overactive RET signal that these tumours use to grow and spread.
Uses of Tanstrive 160mg
Tanstrive 160mg Tablet may be prescribed for selected cancers with RET gene alterations, including certain RET fusion-positive lung and thyroid cancers, RET-mutant medullary thyroid cancer and other eligible RET fusion-positive solid tumours.
How Tanstrive 160mg Tablet works
RET is a protein that signals cells to grow and divide. In certain cancers, changes in the RET gene lead to abnormal RET proteins that drive tumour growth. Tanstrive 160mg Tablet works by blocking this abnormal RET protein, so the cancer cannot grow and spread as easily.
Interaction of Tanstrive 160mg Tablet with other drugs
Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you take.
Acid-reducing medicines may affect absorption.
CYP3A inhibitors may increase Selpercatinib exposure.
CYP3A inducers may decrease its exposure.
Medicines that prolong the QT interval may increase heart rhythm risks.
Selpercatinib can affect certain CYP2C8, CYP3A and P-glycoprotein substrate medicines.
Storage
Store according to the product packaging.
Protect the tablets from moisture.
Keep out of reach of children.
How to use
Take Tanstrive 160mg Tablet exactly as prescribed.
For many adult patients and adolescents weighing 50kg or more, the recommended Selpercatinib dose is 160mg twice daily. Your oncologist may prescribe a different dose depending on your weight, cancer type, liver function and treatment response.
Safety Advice
Pregnancy
Selpercatinib can harm an unborn baby. Effective contraception is recommended during treatment and for the period advised by your doctor.
Breast Feeding
Do not breastfeed during treatment and for the recommended period after the final dose.
Lungs
Report new or worsening cough, breathlessness or other breathing symptoms. Interstitial lung disease or pneumonitis can occur.
Liver
Selpercatinib can cause liver toxicity. Liver enzymes should be monitored during treatment.
Alcohol
No specific direct interaction with alcohol is established. Avoid excessive alcohol and discuss its use with your doctor.
Driving
Use caution if you experience fatigue, dizziness or other symptoms that affect alertness.
Side effects
Common side effects
Oedema
Diarrhoea
Fatigue
Dry mouth
High blood pressure
Abdominal pain
Constipation
Rash
Nausea
Headache
Serious side effects
Liver toxicity
Interstitial lung disease or pneumonitis
QT prolongation
Severe hypertension
Serious bleeding
Hypersensitivity
Tumour lysis syndrome
Impaired wound healing
Seek medical attention promptly for breathing difficulty, severe weakness, confusion, yellowing of the skin or eyes, severe abdominal pain or new neurological symptoms.
Expert Tips
Take the medicine at the same times each day.
Do not change the dose because of side effects without contacting your oncologist.
Keep regular liver, thyroid and blood pressure checks.
Tell your doctor before surgery or dental procedures.
Report severe diarrhoea, breathing difficulty or unusual bleeding.
FAQs
Q1.
What is Tanstrive 160mg tablet used for?
It is used to treat certain RET-positive lung, thyroid, and other solid tumour cancers by blocking the abnormal RET signal that helps these tumours grow.
Q2.
Do I need any tests before starting Tanstrive 160mg tablet?
Yes, your doctor will perform a test to confirm the presence of a RET gene fusion or mutation before starting this medicine.
Q3.
How should I take Tanstrive 160mg tablet?
It is taken by mouth twice a day, generally continued until the disease progresses or side effects become unacceptable.
Q4.
Can Tanstrive 160mg tablet affect my liver?
Yes, increased liver enzymes are a common side effect and can sometimes be serious. Your doctor will monitor your liver function during treatment.
Q5.
Can I use Tanstrive 160mg tablet for children?
Yes, it may be used in children aged 2 years and older for certain thyroid cancers and RET-positive solid tumours, but this should always be decided by your doctor.
Q6.
Can Tanstrive 160mg Tablet cause lung inflammation?
Yes. Interstitial lung disease or pneumonitis can occur. Seek medical advice for new breathing symptoms.
Q7.
Can I stop Tanstrive 160mg Tablet if my cancer symptoms improve?
No. Continue it for the duration prescribed by your oncologist.
Fact box
Molecule name: | Selpercatinib |
Therapeutic class: | Targeted anticancer medicine |
Pharmacological class: | Selective RET kinase inhibitor |
Indications: | RET alteration-positive cancers, including selected lung and thyroid cancers |
References
Disclaimer
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Author Details
Written By
Vishishta
M.Sc Microbiology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 06 Oct 2026 | 09:51 AM (IST)
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