Quick Summary
Tanstrive 80mg Tablet
Last updated on 06 Oct 2026 | 09:10 AM (IST)
₹177435
MRP: ₹215165
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28 TABLET(s) IN A BOTTLE
Tanstrive 80mg Tablet
Salt Composition
SELPERCATINIB
PAP Offer
Buy 2, Get 1 Free. Contact us for latest updates.
Marketer
ELI LILLY AND COMPANY INDIA PVT LTD
18% OFF
₹177435
MRP: ₹2,15,165.00
Inclusive of all taxes
18% Off
Salt Composition
SELPERCATINIB
PAP Offer
Buy 2, Get 1 Free. Contact us for latest updates.
Marketer
ELI LILLY AND COMPANY INDIA PVT LTD
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Introduction
Tanstrive 80mg Tablet contains Selpercatinib as its active ingredient. It is a prescription targeted cancer medicine taken by mouth.
Uses of Tanstrive 80mg
Tanstrive 80mg Tablet may be prescribed for selected cancers with RET gene alterations, including certain RET fusion-positive lung and thyroid cancers and RET-mutant medullary thyroid cancer.
The exact indication depends on the confirmed genetic alteration and the patient's treatment history.
How Tanstrive 80mg Tablet Works
Tanstrive 80mg Tablet contains Selpercatinib, which blocks RET kinase activity. This reduces abnormal signals that can drive the growth of RET-altered cancer cells.
Interaction of Tanstrive 80mg Tablet with Other Medicines
Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you take.
Acid-reducing medicines can affect absorption.
Strong or moderate CYP3A inhibitors can increase Selpercatinib exposure.
Strong or moderate CYP3A inducers can reduce its effectiveness.
Some medicines affecting heart rhythm can increase the risk of QT prolongation.
Selpercatinib can affect certain CYP2C8, CYP3A and P-glycoprotein substrate medicines.
Storage Conditions
Store Tanstrive 80mg Tablet as directed on the product packaging.
Protect the tablets from moisture.
Keep out of reach of children.
How to Use
Take Tanstrive 80mg Tablet exactly as prescribed. Selpercatinib is generally taken twice daily.
The number of tablets required depends on the prescribed total dose. Do not change the dose or combine strengths without your oncologist's advice.
Safety Advice
Pregnancy
Selpercatinib can harm an unborn baby. Effective contraception is recommended during treatment and for the period advised by your doctor.
Breast Feeding
Do not breastfeed during treatment and for the recommended period after the final dose.
Lungs
Report new or worsening cough, breathlessness or other breathing symptoms. Interstitial lung disease or pneumonitis can occur.
Liver
Selpercatinib can cause liver toxicity. Liver enzymes should be monitored during treatment.
Alcohol
No specific direct interaction with alcohol is established. Avoid excessive alcohol and discuss its use with your doctor.
Driving
Use caution if you experience fatigue, dizziness or other symptoms that affect alertness.
Side Effects
Common side effects
Oedema
Diarrhoea
Fatigue
Dry mouth
High blood pressure
Abdominal pain
Constipation
Rash
Nausea
Headache
Serious side effects
Liver toxicity
Pneumonitis
QT prolongation
Severe hypertension
Serious bleeding
Hypersensitivity
Tumour lysis syndrome
Wound-healing problems
Seek medical attention promptly for breathing difficulty, severe weakness, confusion, yellowing of the skin or eyes, severe abdominal pain or new neurological symptoms.
Expert Tips
Do not take acidity medicines without checking with your doctor.
Monitor blood pressure as advised.
Keep scheduled liver and thyroid tests.
Tell your doctor before planned surgery.
Report breathing problems or unusual bleeding promptly.
FAQs
Q1.
What is Tanstrive 80mg Tablet used for?
It is used for selected cancers with RET gene alterations.
Q2.
How often should Tanstrive 80mg Tablet be taken?
Selpercatinib is generally taken twice daily, with the total dose determined by the doctor.
Q3.
Can Tanstrive 80mg Tablet be taken with antacids?
Acid-reducing medicines can affect Selpercatinib absorption. Ask your doctor or pharmacist about the correct timing.
Q4.
Does Tanstrive 80mg Tablet affect blood pressure?
Yes. High blood pressure can occur during treatment.
Q5.
Does Tanstrive 80mg Tablet affect the liver?
It can. Regular liver function monitoring may be required.
Q6.
Can Tanstrive 80mg Tablet cause lung problems?
Yes. Contact your doctor promptly if you develop new cough or breathing difficulty.
Q7.
Can I stop Tanstrive 80mg Tablet when I feel better?
No. Continue treatment for the duration prescribed by your oncologist.
Fact Box
Molecule name: | Selpercatinib |
Therapeutic class: | Targeted anticancer medicine |
Pharmacological class: | Selective RET kinase inhibitor |
Indications: | RET alteration-positive cancers, including selected lung and thyroid cancers |
References
Disclaimer
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Author Details
Written By
Vishishta
M.Sc Microbiology

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 06 Oct 2026 | 09:10 AM (IST)

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