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Velcade 3.5mg Injection

Prescription Required
bortezomib

44063

MRP: 50953.13

(You Save ₹6890.13)

1 VIAL(s)

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Velcade 3.5mg Injection
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44063

MRP: 50,953.13

Inclusive of all taxes

14% Off

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1 Vial(s)

1 Vial(s)

44063.0/Unit
Prescription Required
Prescription Required

Salt Composition

BORTEZOMIB

Marketer

JOHNSON & JOHNSON PVT LTD

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Introduction

Velcade 3.5mg Injection contains bortezomib, a chemotherapy medicine classified under proteasome inhibitors. It is primarily used to treat multiple myeloma and mantle cell lymphoma, two types of blood cancer. Velcade is often used in combination with other chemotherapy medicines such as doxorubicin, cyclophosphamide, dexamethasone, thalidomide, or rituximab, especially in patients who have not yet undergone or are not eligible for stem cell transplantation.

This medicine works by blocking the proteasome system inside cells, which plays a vital role in removing damaged proteins. By inhibiting this function, Velcade causes the accumulation of toxic proteins inside cancer cells, leading to their death. This helps in controlling the spread and growth of cancer cells.

Velcade can be administered through different routes, and doctors decide the method based on the treatment plan. A common patient query is Velcade 3.5 mg subcutaneous vs IV, where subcutaneous injection (under the skin) is often preferred in many cases due to improved tolerability, while IV (intravenous) administration may be used depending on hospital protocol. The oncologist also plans the Velcade 3.5mg injection dosage cycle based on the patient’s condition, response, and combination therapy schedule.

Many patients also ask about availability, pricing, and alternatives. The Velcade 3.5 mg price in India can vary depending on stock, city, and supplier. Some users try to calculate Velcade 3.5mg vial price 1mg, but Velcade is usually available as a complete vial (3.5mg), and pricing is generally determined per vial. If you are looking to Buy Velcade 3.5mg online, it is important to purchase only from a licensed pharmacy that ensures prescription verification, genuine sourcing, and proper billing.

In India, multiple options are available for bortezomib. Patients commonly compare Bortenat 3.5mg vs Velcade 3.5mg, where Velcade is the original branded product, while Bortenat is one of the generic bortezomib brands. Other substitutes include Bortecad and Borviz. If you are searching for Generic Velcade 3.5 mg India, it typically refers to Indian brands that contain the same active ingredient (bortezomib 3.5mg) and may be recommended when clinically appropriate.

Another important point is handling and transport, especially for speciality oncology drugs. Velcade 3.5mg cold chain storage requirements depend on label instructions and pharmacy protocols, and proper temperature-controlled handling is essential to maintain medicine quality. If you are ordering online, confirm that cold-chain logistics are followed wherever required.

Lastly, patients may also want to know about sourcing and authenticity. Velcade 3.5mg injection manufacturers can include the innovator brand and authorised suppliers, while generic bortezomib is produced by multiple Indian pharma companies. Always ensure the vial has intact packaging, batch number, expiry date, and proper invoice to guarantee authenticity and safety.

Uses

Velcade 3.5mg injection uses:

How Velcade Injection Works

Velcade blocks a protein complex called the 26S proteasome, which plays a key role in regulating protein breakdown inside cells. This blockage causes damaged proteins to accumulate in cancer cells, disrupting their function and triggering cell death (apoptosis). It also helps enhance the effects of other chemotherapy drugs and reduces cancer cell growth.

Interaction of Velcade 3.5mg Injection with other drugs

Inform your doctor about all medications you’re taking, including:

  • Phenytoin, fosphenytoin, carbamazepine (may reduce effectiveness of Velcade)

  • Herbal supplements and vitamin preparations

These interactions may require dose adjustments or close monitoring.

Storage Conditions

  • Store velcade 3.5 mg vial in a refrigerator (2°C – 8°C).
  • Do not freeze.
  • Protect the medicine from light and excessive moisture.
  • Keep the medicine out of reach of children and pets
  • It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

How to Use Velcade 3.5mg Injection

Velcade is administered intravenously (into a vein) or subcutaneously (under the skin) by a trained healthcare professional. The dose and schedule depend on your medical condition, body weight, and response to treatment. Do not self-administer this medicine. If you miss a scheduled Velcade dosage, inform your doctor immediately—do not double the dose to catch up.

Safety Advice for Velcade 3.5mg Injection

Breast Feeding-unsafe

Breast Feeding

Unsafe

It is not recommended to use Velcade 3.5mg injection during breastfeeding. Your physician will prescribe it only if necessary. You should consult your physician regarding the safe period to restart breastfeeding after this treatment.

Alcohol-unsafe

Alcohol

Unsafe

Velcade 3.5mg injection is metabolized in the liver, and excessive alcohol consumption can also lead to liver damage. The use of two concomitantly may potentially increase the risk of liver problems.

Liver-Consult your doctor

Liver

Consult Your Doctor

Velcade 3.5mg injection should be taken cautiously in patients with liver problems. If you have liver disease or an infection with hepatitis, let your doctor know before beginning this treatment. Your doctor will periodically check on the health of your liver.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

Velcade 3.5mg injection should be used with caution in individuals who have respiratory issues. Let your doctor know if you have any lung conditions before starting any treatment.

Driving-unsafe

Driving

Unsafe

Velcade 3.5mg injection may impair your ability to operate machinery, ride a bike, or drive. After taking this medication,tiredness, dizziness and blurred vision are expected.If a patient experiences any side effects that affect their ability to drive or operate machinery safely while taking Velcade 3.5mg injection , they should avoid these activities and seek medical advice.

Pregnancy-unsafe

Pregnancy

Unsafe

Velcade 3.5mg injection should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 3 months after the last dose.

Side Effects

Velcade 3.5mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Velcade 3.5mg injection side effects:

Serious:

  • Peripheral neuropathy

  • Hypotension

  • Cardiac toxicity

  • Posterior Reversible Encephalopathy Syndrome (PRES)

  • Tumor Lysis Syndrome

  • Hepatic Toxicity

  • Thrombotic Microangiopathy

Common:

  • Loss of appetite

  • Sensitivity, tingling and burning sensation of the skin

  • Nausea, vomiting, and diarrhea

  • Mouth ulcers

  • Constipation

  • Muscle and bone pain

  • Hair loss

  • Fever

  • Reduction in blood cell count

  • Reduced kidney function

  • Shivering

  • Infections

  • Dehydration

  • Stomach problems

  • Difficulty sleeping, anxiety, mood swings, depressed mood

Expert Tips

  • Stay hydrated and eat a balanced diet to support recovery.

  • Include anti-inflammatory and antioxidant-rich foods like fruits, vegetables, olive oil, and nuts.

  • Avoid vaccinations without your doctor’s advice during treatment.

  • Do not miss follow-up appointments or routine blood tests.

  • Inform your doctor if you have or have had hepatitis B, even if inactive.

FAQs about Velcade 3.5mg Injection

Q1.

I have an infection with hepatitis. Is Velcade 3.5mg injection safe to take?

Patients with active hepatitis should not take boratezamib. because they may experience recurrent, potentially fatal cases of hepatitis. Your doctor will closely monitor you for signs of active hepatitis B if you have a history of the infection.

Q2.

Can I take Velcade 3.5mg injection when I am pregnant?

Avoid taking Velcade 3.5mg injection if you are pregnant, as it can cause harmful effects on the unborn baby. Females should use effective birth control methods during treatment and at least three months after treatment.

Q3.

What are the common side effects of Velcade 3.5mg injection?

Common side effects of adalimumab may include injection site reactions, such as pain, redness, or swelling. Other possible side effects include loss of appetite, sensitivity, tingling and burning sensation of the skin, nausea, vomiting, and diarrhea, constipation Serious side effects are rare but can occur.

Q4.

How long can I take Velcade 3.5mg injection?

The duration of Velcade 3.5mg injection treatment can vary depending on the individual's condition and response to the medication. In some cases, this medicine may be used as a long-term maintenance therapy, while treatment duration may be shorter in other situations. It is important to follow the healthcare provider's guidance regarding the appropriate duration of treatment.

Q5.

Can Velcade 3.5mg injection be used in individuals with kidney or liver impairment?

Velcade 3.5mg injection may require dosage adjustments or caution in individuals with kidney or liver impairment. Healthcare providers will assess the patient's situation and determine the appropriate dosage based on renal and hepatic function.

Q6.

What parameters will be monitored during treatment with Velcade 3.5mg injection?

During treatment with Velcade 3.5mg injection, your health care provider will monitor RBC, WBC, platelets, liver, blood glucose and kidney parameters.

Fact Box

Molecule name: 

Bortezomib

Therapeutic class:

Antineoplastic agents

Pharmacological class:

 Proteasome inhibitors

Indications: 

1.  Treatment of multiple myeloma

2. Treatment of mantle cell lymphoma

Dosage form:  

Injections

Habit forming: 

No


 

References

  1. Tillomed Laboratories Ltd, Electronics Medicines Compendium(emc), [ Revised on November 2022] [ Accessed on 02-04-2024], https://www.medicines.org.uk/emc/files/pil.12587.pdf
  2. MAIA Pharmaceuticals, Inc,  United States Food and Drug Administration (US FDA), [ Revised on July 2022] [Accessed on 02-04-2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/215331s000lbl.pdf
  3. Pfizer, [Accessed on 02-04-2024],  https://labeling.pfizer.com/ShowLabeling.aspx?id=15338
  4. Dr. Reddy’s Laboratories Limited, [Revised on April 2016], [Accessed on 02-04-2024], https://www.drreddys.com/media/503329/bortezomib-en.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that experts, accurate and trustworthy, review. The information and contents of this website are for informational purposes only. They are not intended to substitute for professional medical advice, diagnosis, or treatment. Please seek your doctor's advice and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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