Apigy 2.5mg Tablet uses are

• Prophylaxis of Deep vein thrombosis (DVT)

• Prevent blood clots

It is a direct oral anticoagulant (DOAC) that works by inhibiting the activity of factor Xa, which is a protein involved in the blood clotting process. Specifically, this drug binds to the active site of factor Xa and blocks its ability to convert prothrombin to thrombin. This, in turn, prevents the formation of blood clots.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Apigy 2.5mg Tablet and reduce effectiveness by causing undesirable side effects. 

• Store Apigy 2.5mg Tablet in a controlled room temperature (20°C to 25°C).

• Keep it out of reach from children.

Your doctor will decide the dose and duration of Apigy 2.5mg Tablet based on the disease condition. Always take this medicine as prescribed by your doctor. The recommended starting oral dose of axitinib is 2.5 mg twice daily. Take the tablet at the same time everyday, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Apigy 2.5mg Tablet side effects are

Serious

• Allergic reactions

• Abnormal liver function

• Low blood pressure, fainting

• Bleeding in vagina, stomach, nose, red stools.

• Allergic reactions like swelling in lips, face, throat.

• Bleeding in brain

Common

• Skin rash

• Hair loss

• Itching

• Reduced number of platelets

• This tablet increases the risk of bruising, so take extra care when handling sharp objects or doing activities that may cause injury.

• Always inform your doctor before any medical procedure, including dental work or surgery, so that necessary precautions can be arranged in advance.

• Let your doctor know about all other medications you are currently taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid potential interactions.

• Eat a diet rich in fibre, including fruits, vegetables, and whole grains, to help regulate bowel movements and reduce the risk of constipation, which can increase bleeding risk.

1. Bristol Myers Squibb/Pfizer EEIG; Electronic Medicines Compendium; [Revised:2021] [Accessed on 03/Apr/2023] https://www.medicines.org.uk/emc/files/pil.4756.pdf
2. Highlights of prescribing information; food and drug administration. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/211964s000lbl.pdf  [Accessed on 03/Apr/2023].
3. Annex I summary of Product Characteristics - European Medicines Agency; Available at: https://www.ema.europa.eu/en/documents/product-information/eliquis-epar-product-information_en.pdf [Accessed on 03/Apr/2023].
4. Katherine Victoria Hurst, John Matthew O’Callaghan and Ashok Handa; ; Quick reference guide to Apixaban; Published 2017 [Accessed on 03/Apr/2023].https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5513886/#__ffn_sectitle
5. SL Greig; Apixaban: A review in venous thromboembolism; [Published:2016] [Accessed on 03/Apr/2023] https://pubmed.ncbi.nlm.nih.gov/27653758/
6. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics,Modulation of Cardiovascular Function, 12th edition, 2011, 867.
7. Bertram.G.Katzung, Basic and Clinical Pharmacology, Drugs Used to Treat Diseases of the Blood, Inflammation, & Gout, 14th edition, 617.