MEGAHENZ 40MG TABLET

Introduction:

Megahenz 40mg Tablet contains the active substance Megestrol. It belongs to a category of medications called progestogens and is used to treat certain hormone-dependent cancers, such as breast cancer. It is a synthetic form of the naturally occurring progesterone hormone. It is also indicated to treat unexplained weight loss, weakness and loss of appetite in patients with weak immune system and cancer.

Progestogen therapy is useful for patients whose disease has progressed with conventional anti-estrogen therapy. Your physician will assess the estrogen status (ER) to ensure that your breast cancer is due to the expression of the estrogen receptor.

Uses of Megahenz 40mg Tablet:

Megahenz 40mg Tablet is used to treat the following conditions:

• Hormone-dependent cancer (endometrial cancer, breast cancer)
• Unexplained weight loss, weakness and loss of appetite in patients with weak immune system and cancer.

How Megahenz 40mg Tablet works:

Megahenz 40mg Tablet exhibits anticancer properties by interacting with steroidal receptors. It suppresses steroid production by the adrenal glands and androgen secretion by the ovaries in postmenopausal women. It also prevents the breakdown of cytokines and stimulates appetite in chronic disease-induced anorexia and cachexia.

Interaction with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More Information:

Store at a temperature below 25°C, protected from light and moisture. Keep medicine out of reach of children.

References:

1. Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
2. alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
3. Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
4. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.

How to use Megahenz 40mg Tablet:

Swallow the tablet whole with water. Your physician will decide the ideal dose for you, depending on your condition.

Safety Advice:

Pregnancy:

This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant. 

Breastfeeding: 

Consult your physician before taking this tablet if you are a breastfeeding mother.

Liver:

Inform your physician before starting this treatment if you have liver problems. Your physician will monitor your liver functions regularly.

Kidney:

Inform your physician before starting this treatment if you have kidney diseases. Your physician will monitor your kidney functions regularly if you are above 65 years of age.

Driving: 

Avoid driving or using machinery if you experience side effects.

Allergies: 

Inform your physician if you experience allergic reactions to Megestrol or other ingredients of this medicine.

Others:

• Inform your physician before taking this medicine if you have suffered from blood clots.
• This medicine could increase your blood sugar levels. Inform your physician if you have diabetes.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Swelling of the face, lips, tongue
• Skin rash
• Breathing difficulty
• Blood clot in the lungs
• Heart problems

Common:

• Weight gain and increased appetite
• Hot flushes
• High BP
• High blood sugar levels
• Rounded face
• Constipation
• Swelling of vein
• Mood changes
• Hair loss
• Diarrhea
• Tiredness and weakness
• Impotence
• Passing wind
• Frequent urination
• Nausea, vomiting
• Fluid accumulation
• Pain

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