Semaneo 1mg Pen Injection is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Semaglutide may be used alone when metformin-based treatment is not suitable because of intolerance or contraindications, or together with other medicines used to treat diabetes, as prescribed by the doctor.

Semaglutide works by mimicking the action of GLP-1, a naturally occurring hormone involved in blood glucose regulation. It increases insulin release when blood glucose levels are elevated, reduces glucagon secretion and slows stomach emptying. These effects help lower blood glucose levels and improve glycaemic control.

Tell your doctor about all the medicines you take before starting Semaneo 1mg Pen Injection.

• Insulin and sulfonylureas: Using semaglutide with these medicines may increase the risk of low blood sugar. Your doctor may adjust the dose of the other medicine.

• Other semaglutide-containing medicines: Do not use Semaneo with another medicine containing semaglutide unless specifically prescribed.

• Other GLP-1 receptor agonists: Combining Semaneo with another GLP-1 receptor agonist is not recommended.

• Oral medicines: Semaglutide delays gastric emptying and may affect the absorption of some medicines taken by mouth. Tell your doctor about medicines that require careful monitoring.

• Store Semaneo 1mg Pen Injection in a refrigerator at 2°C to 8°C.

• Do not freeze the pen.

• Keep it away from the cooling element of the refrigerator.

• Keep the pen cap on when the pen is not being used to protect it from light.

• After first use, store the pen below 30°C or in a refrigerator at 2°C to 8°C, as stated on the product packaging.

• Discard the pen 6 weeks after first use, even if some solution remains.

• Keep it out of the reach of children.

Semaneo 1mg Pen Injection is administered under the skin once a week. It can be injected into the abdomen, thigh or upper arm. It may be administered at any time of day, with or without food. Use it on the same day each week as advised by your doctor.

The 1mg dose is generally reached after treatment has been started at a lower dose and increased gradually. Do not change the dose or frequency without medical advice.

The pen should be inspected before use. Do not use it if the solution is not clear and colourless or if you notice particles in it.

Common side effects of Semaglutide include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

These effects are more likely during dose escalation and may reduce as the body adjusts to treatment.

Seek medical attention if you develop severe or persistent abdominal pain, symptoms of a serious allergic reaction, significant changes in vision or symptoms of severe dehydration. Semaglutide is also associated with important risks including pancreatitis, diabetic retinopathy complications and gallbladder problems.

• Use Semaneo exactly as prescribed by your doctor.

• Take your weekly dose on the same day each week.

• Do not increase the dose without medical advice.

• Continue your prescribed diet and physical activity plan.

• If you experience nausea, eating smaller meals and avoiding very fatty foods may help.

• Drink enough fluids, particularly if vomiting or diarrhoea occurs.

• Monitor your blood glucose as advised by your doctor.

• Tell your doctor that you use Semaneo before undergoing surgery or deep sedation.

• Do not share your pen with another person, even if the needle has been changed.