Semaneo 0.25mg Pen Injection is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

The 0.25mg dose is generally used as the initial dose of semaglutide treatment rather than as a maintenance dose. The dose may be increased gradually according to the treatment plan prescribed by the doctor.

Semaglutide acts like GLP-1, a hormone that helps regulate blood glucose levels. It increases insulin release when blood glucose is high and reduces the release of glucagon, a hormone that raises blood glucose.

It also slows gastric emptying, which can reduce the rate at which glucose enters the bloodstream after meals. Together, these actions help improve blood sugar control.

Tell your doctor about all medicines you take before using Semaneo 0.25mg Pen Injection.

• Insulin and sulfonylureas: Semaglutide can increase the risk of low blood sugar when used with insulin or sulfonylureas. Your doctor may adjust the dose of these medicines.

• Other semaglutide-containing medicines: Do not use Semaneo with another medicine containing semaglutide.

• Other GLP-1 receptor agonists: Combining Semaneo with another GLP-1 receptor agonist is not recommended.

• Oral medicines: Semaglutide slows gastric emptying and may affect the absorption of some medicines taken by mouth. Tell your doctor about medicines that require close monitoring.

• Store Semaneo 0.25mg Pen Injection in a refrigerator at 2°C to 8°C.

• Do not freeze the pen.

• Keep it away from the cooling element of the refrigerator.

• Protect the pen from light.

• Keep it out of the reach of children.

• Do not use the medicine if it has been frozen or if the solution appears abnormal.

Semaneo 0.25mg Pen Injection is administered under the skin once a week. It can be injected into the abdomen, thigh or upper arm. It can be used at any time of day, with or without food. Try to administer it on the same day each week.

The usual starting dose of semaglutide is 0.25mg once weekly. After four weeks, the dose is generally increased to 0.5mg once weekly if prescribed by the doctor. The gradual increase helps improve gastrointestinal tolerability. Do not change the dose or injection schedule without medical advice.

Before each injection, check the solution through the pen window. It should be clear and colourless. Do not use the pen if the solution is cloudy, coloured or contains particles.

The most common side effects of semaglutide include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

These effects are particularly common when treatment is started or the dose is increased and often become less troublesome as the body adjusts to the medicine.

Contact your doctor if you develop severe or persistent abdominal pain, repeated vomiting, signs of dehydration, changes in vision or symptoms of a serious allergic reaction. Semaglutide can also cause or worsen certain complications involving the pancreas, gallbladder, kidneys and eyes.

• Use Semaneo exactly as prescribed by your doctor.

• The 0.25mg dose is generally used to start treatment. Do not increase the dose on your own.

• Take the injection once a week, preferably on the same day each week.

• Follow the diet and physical activity plan recommended by your doctor.

• Eating smaller meals may help reduce nausea and stomach discomfort.

• Drink enough fluids, especially if you have vomiting or diarrhoea.

• If you use insulin or a sulfonylurea, monitor your blood glucose as advised.

• Tell your doctor that you use semaglutide before planned surgery or deep sedation.

• Never share your injection pen with another person.