Usema 2mg Injection is used to:

• Improve blood sugar control in type 2 diabetes mellitus: It helps lower blood glucose levels along with diet and exercise.

• Support ongoing diabetes management: It may be prescribed alone or with other diabetes medicines when additional blood sugar control is needed.

Usema is not used to treat type 1 diabetes or diabetic ketoacidosis.

Usema 2mg Injection contains Semaglutide, which acts like GLP-1, a natural hormone involved in blood sugar regulation.

It increases insulin release when blood sugar levels are high and reduces glucagon release. It also slows stomach emptying and can increase feelings of fullness. Together, these effects help improve blood sugar control.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you take.

• Insulin or sulfonylureas: These medicines can increase the risk of low blood sugar when used with Semaglutide.

• Oral medicines: Semaglutide slows stomach emptying and may affect the absorption of some medicines taken by mouth.

• Warfarin or other coumarin medicines: Your doctor may recommend closer monitoring after Semaglutide is started.

• Other GLP-1 receptor agonists: Do not combine Usema with another Semaglutide-containing medicine or GLP-1 receptor agonist unless specifically prescribed.

• Store Usema 2mg Injection in a refrigerator at 2°C to 8°C before use.

• Do not freeze the pen.

• Do not use it if it has been frozen.

• Protect the pen from light.

• Keep it out of the sight and reach of children.

• Follow the product packaging for instructions after first use.

Use Usema 2mg Injection exactly as prescribed by your doctor.

The 2 mg/1.5 mL pen is designed to deliver 0.25 mg or 0.5 mg doses. It is administered under the skin once a week and may be given at any time of the day, with or without food.

Inject it into the abdomen, thigh or upper arm. Rotate injection sites when possible.

The 0.25 mg dose is generally used when starting Semaglutide treatment, followed by a gradual increase when appropriate. Your doctor will decide the dose according to your blood sugar control and tolerance.

Do not inject Usema into a vein or muscle and do not share the pen with another person.

Common side effects of Usema 2mg Injection may include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

• Decreased appetite

• Indigestion

• Headache

• Dizziness

• Fatigue

Serious side effects:

• Severe and persistent abdominal pain, which may indicate pancreatitis.

• Persistent vomiting or diarrhoea leading to dehydration or kidney problems.

• Gallstones or gallbladder inflammation.

• Severe allergic reactions, including swelling or difficulty breathing.

• Severe low blood sugar when used with insulin or sulfonylureas.

• Sudden or worsening changes in vision.

• Severe gastrointestinal symptoms, particularly in people with delayed stomach emptying.

Seek medical attention if serious symptoms develop.

• Use Usema exactly as prescribed.

• Do not increase the dose without medical advice.

• Follow your recommended diet and physical activity plan.

• Drink enough fluids if you experience vomiting or diarrhoea.

• Rotate injection sites.

• Tell your doctor about diabetic retinopathy or any new vision changes.

• Tell your doctor if you have severe problems with delayed stomach emptying.

• Inform your healthcare team before surgery or deep sedation.

• Tell your doctor if you have a personal or family history of medullary thyroid carcinoma or MEN 2.

• Never share the pen.