Semalix 4mg Injection is used to:

• Improve blood sugar control in adults with type 2 diabetes mellitus: It is used along with diet and exercise.

• Support chronic weight management: It may be prescribed for eligible adults with obesity or overweight with at least one weight-related health condition, according to the approved indication.

Semalix 4mg Injection contains Semaglutide, which mimics the action of GLP-1, a hormone involved in blood sugar and appetite regulation.

It increases insulin release when blood sugar is elevated and reduces glucagon release. It also slows stomach emptying and may increase feelings of fullness. These effects help improve blood sugar control and can reduce food intake.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements and herbal products you take.

• Insulin or sulfonylureas: These may increase the risk of low blood sugar when combined with Semalix.

• Oral medicines: Delayed stomach emptying may affect the absorption of some oral medicines.

• Warfarin or other coumarin medicines: Your doctor may recommend closer INR monitoring after treatment begins.

• Other GLP-1 receptor agonists: Do not combine Semalix with another Semaglutide-containing medicine or GLP-1 receptor agonist unless prescribed.

• Store Semalix 4mg Injection in a refrigerator at 2°C to 8°C.

• Do not freeze the medicine.

• Do not use it if it has been frozen.

• Protect the pen from light.

• Keep it out of the reach of children.

• Follow the product packaging for storage instructions after first use.

Use Semalix 4mg Injection exactly as prescribed by your doctor.

The 4 mg/3 mL prefilled pen is designed to deliver a 1 mg dose. It is administered under the skin once a week, with or without food.

The injection may be given in the abdomen, thigh or upper arm. Rotate injection sites to reduce local irritation.

Your doctor may increase the dose gradually depending on your response and tolerance. Do not change the prescribed dose yourself.

Do not inject Semalix into a vein or muscle. Do not share the pen with another person.

Common side effects of Semalix 4mg Injection may include:

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Abdominal pain

• Indigestion

• Decreased appetite

• Headache

• Dizziness

• Fatigue

Serious side effects:

• Severe or persistent abdominal pain, sometimes spreading to the back, which may indicate pancreatitis.

• Persistent vomiting or diarrhoea causing dehydration or kidney problems.

• Gallstones or inflammation of the gallbladder.

• Severe allergic reactions, including swelling of the face, lips, tongue or throat or difficulty breathing.

• Severe low blood sugar when used with insulin or sulfonylureas.

• Sudden loss or worsening of vision.

• Severe gastrointestinal reactions, particularly in people with delayed stomach emptying.

Semalix product information also advises urgent assessment for sudden loss of vision and caution in people with diabetic retinopathy.

• Use Semalix exactly as prescribed.

• Do not change the dose without medical advice.

• Follow your recommended diet and physical activity plan.

• Drink enough fluids if vomiting or diarrhoea occurs.

• Rotate injection sites.

• Tell your doctor about diabetic retinopathy or any vision changes.

• Tell your doctor if you have severe problems with delayed stomach emptying.

• Inform your healthcare team before surgery or deep sedation.

• Tell your doctor if you have a personal or family history of medullary thyroid carcinoma or MEN 2.

• Do not share your pen.